The Aqueous Extract of Withania coagulans Fruit Partially Reverses Nicotinamide/Streptozotocin-Induced Diabetes Mellitus in Rats

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Withania coagulans Fruit Extract Reduces Oxidative Stress and Inflammation in Kidneys of Streptozotocin-Induced Diabetic Rats

The present study was carried out to investigate the changes in oxidative and inflammatory status in streptozotocin-induced diabetic rat's kidneys and serum following treatment with Withania coagulans, a popular herb of ethnomedicinal significance. The key markers of oxidative stress and inflammation such as inflammatory cytokines (IL-1β, IL-6, and TNF-α) and immunoregulatory cytokines (IL-4 an...

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Hypolipidemic and antioxidant activity of aqueous extract of fruit of Withania coagulans (Stocks) Dunal in cholesterol-fed hyperlipidemic rabbit model.

Withania coagulans (family: Solanaceae, English: Indian Cheese Maker, Hindi: Doda Paneer) fruit is known for its ethanopharmacological significance in health care system of India. Diet rich in high-fat is an important risk factor for diabetes, atherosclerosis and macro and microvascular complications. Treatment with aqueous extract of fruit of W. coagulans (aqWC; 250 mg/kg body weight) in chole...

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Antidiabetic Efficacy of Aqueous Fruit Extract of Amla (Emblica officinalis, Gaertn) in Streptozotocin-Induced Diabetes Mellitus in Male Rats

Purpose: To investigate the antidiabetic potential of Emblica officinalis, Gaertn on diabetic rats. Methods: The study investigated the anti-hyperglycemic potential of the aqueous fruit extract of amla (E. officianalis, for eleven weeks in streptozotocin-induced diabetic obese rats. The study utilized forty eight rats divided into four groups as follows. Untreated diabetic control (group 1) rec...

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Effects of the Aqueous Seed Extract of Withania somnifera ( Ashwagandha ) against Pilocarpine - induced Convulsions in Rats

The present study is designed to investigate effect of Ashwagandha aqueous seed extract against pilocarpine-induced convulsions in rats. Convulsions was induced by pilocarpine injection (300mg/kg, i.p.). After 15 days, the animals were received carbamazepine (100 mg/kg) and Ashwagandha (25 & 50 mg/kg, orally), for 14 days. Death, latencies to the first convulsion and cholinergic signs were obse...

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ژورنال

عنوان ژورنال: Journal of Medicinal Food

سال: 2012

ISSN: 1096-620X,1557-7600

DOI: 10.1089/jmf.2011.1829